January 2022
Subgingival irrigation with phytotherapics adjunct to scaling and root planing on the treatment of experimental periodontal disease in rats
Abstract
Aim: To evaluate subgingival irrigation with Matricaria recutita (MAT) and Plantago major (PLA) adjunct to scaling and root planing (SRP) on treatment of experimental periodontitis (EP). Design: EP was induced in 72 rats. After 7 days, animals were randomly distributed in groups: SRP – SRP and irrigation with saline; MAT - SRP and irrigation with MAT solution; and PLA - SRP and irrigation with PLA solution. Euthanasia was performed after 7, 15 and 30 days (n=8). It was evaluated colony-forming units (CFU), bone loss (BL), percentage of mature and immature collagen fibers, TRAP, RANKL and OPG (p <0.05). Results: Groups MAT and PLA had significantly lower number of CFU than Group SRP (15 days). Group PLA had significantly lower BL than Group MAT (7 days). Group MAT had significantly higher percentage of immature collagen fibers than groups SRP and PLA (15 days). Group PLA presented significantly higher OPG than Group SRP (7 days) and significantly lower RANKL than groups MAT and SRP (15 days). Conclusions: Combine MAT or PLA with SRP to treat EP presented additional antimicrobial and anti-inflammatory effects when compared to SRP. However, PLA presented significantly higher collagen maturation and protective effect against bone resorption than MAT.
Other articles in this issue
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| Machine learning identification of periodontitis patients and their subgingival microbial features Natalia Sánchez-Lopera, Manuela Restrepo-Posada, Sthefania Gutiérrez-González, David Ortega-Valderrama, Sandra Amaya-Sánchez, Adolfo Contreras, Andrés Felipe Gutiérrez, Leonardo A. Pachon, Javier Enrique Botero | Download |
| Epidemiology of periodontitis in Brazilian adults: an integrative literature review of large and representative studies Tayse Caroline Cunha de Medeiros, Alessandra Areas e Souza, Alex Nogueira Haas, João Paulo Steffens | Download |
| Effect of age on expression of osteoclastogenic bone biomarkers in periodontal surgical treatment outcomes Priyanka Gupta, Rameshwari Singhal, Pavitra Rastogi, Nand Lal, Anjani Kumar Pathak, Shivani Pandey, Abbas Ali Mahdi | Download |
| Correlation of periodontal ligament associated protein-1 and tumour necrosis factor – alpha levels in gingival crevicular fluid and serum in periodontal health and diseased subjects before and after nonsurgical periodontal therapy Ankitha Menon, Athira Jayan, AR Pradeep | Download |
| Factors affecting demand for dental implant treatment: a patient-centered observational study Nil Yakar, Onurcem Duruel, Güliz N. Güncü, Erdem Karabulut, Nermin Yamalik | Download |
| Antibiotics plus probiotic as an adjunct to the treatment of periodontitis in smokers: a short-term study Leticia H. Theodoro, João M. Mello-Neto, Marina M. Cláudio, Marta A. A. Nuernberg, Daniela M. J. Miessi, Beatriz G. Silva, João Victor S. Rodrigues, Daniela A. Brandini, Valdir G. Garcia | Download |
| Subgingival irrigation with phytotherapics adjunct to scaling and root planing on the treatment of experimental periodontal disease in rats Carolina dos Santos Santinoni, Marcela Lucio Caldeira, Taciane Menezes da Silveira, Bibiana Dalsasso Velasques, Natália Marcumini Pola, Christine Men Martins, Douglas Roberto Monteiro, Luciana Prado Maia, Edilson Ervolino, Thiago Marchi Martins | Download |
| Vegetarian diet and periodontal status: assessment of clinical measures and gingival fluid inflammatory cytokines Ahmed Khocht, Michael Orlich, Denise Bellinger, Leticia Lenoir, Crissy Irani, Gary Fraser | Download |
| Platelet-rich fibrin as palatal bandage in gingival graft harvest: a systematic review and meta-analysis Agnes Andrade Martins, Jaiane Carmélia Monteiro Viana, Rayrane Iris Melo da Cunha, Luanny de Brito Avelino, Maria Helena Rodrigues Galvão, Cristiano Miranda de Araújo, Karinna Veríssimo Meira Taveira, Gustavo Henrique Apolinário Vieira | Download |
