July 2020
Effect of Adjunctive Probiotic Therapy on the Treatment of Peri-implant Diseases – A Systematic Review
Abstract
Aim: The aim of this study was to determine the effects of probiotics on peri-implant diseases. Materials and Methods: PubMed-MEDLINE, Scopus, Literature in the Health Sciences in Latin America and the Caribbean (LILACS) and Science Direct were searched until September 2019. Three authors independently carried out this search, using the following search algorithm to explore databases using Boolean operators (“peri-implant diseases” OR “dental implants”) AND (“probiotics” OR “lactobacillus”). Randomized clinical trials were included. No limits were applied to the year and articles were restricted to those in the English, Spanish and Portuguese languages. Review articles, reports of clinical cases and works without mention of the topic were excluded. Results: Five randomized clinical trials were analyzed in the final review process. For the primary outcomes - Periodontal probing depth (PPD) and bleeding on probing (BOP); and for the secondary outcames - plaque index, gingival index, gingival crevicular fluid and microbiological tests - no significant clinical effects of probiotics were observed. Conclusion: Probiotics could be used during the treatment of peri-implant diseases. However, the most appropriate form of probiotic administration or the effectiveness of this approach are still unclear. There is currently insufficient evidence to demonstrate the benefits of the use of probiotics as an adjunctive therapy in patients with peri-implant diseases
Other articles in this issue
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| Gingival Crevicular Fluid Levels of Human Beta-defensin 2 and 3 in Healthy and Diseased Sites of Individuals with and without Periodontitis Alexandre Godinho Pereira, Lidiane Cristina Machado Costa, Kahena Rodrigues Soldati, Mauro Henrique Nogueira Guimarães de Abreu, Fernando Oliveira Costa, Daniela Leal Zandim- Barcelos and Luís Otávio Miranda Cota | Download |
| Quality Assessment of Randomized Clinical Trials in Periodontal Research from 2015- 2018 - A Cross Sectional Analysis Abdullah Saleh Al Mutairi and Muzammil | Download |
| Alveolar Ridge Regeneration of Damaged Extraction Sockets using a Bovine-derived Bone Graft in Association with a Titanium Foil: Prospective Case Series Danilo Maeda, Fernando Lima, Jonathan Meza, Danilo Lazzari Ciotti, Fabio Shiniti Mizutani, Helio Doyle, Marcelo Faveri | Download |
| Clinical Evidence for Treatment of Class II Periodontal Furcation Defects. Systematic Review and Meta-analysis Hiskell Fernandes e Oliveira, Fellippo Verri, Cleidiel Aparecido Lemos, Ronaldo Cruz, Victor Eduardo de Souza Batista, Eduardo Pellizzer and Carolina Santinoni | Download |
| One-Stage Full Mouth Instrumentation (OSFMI): Clinical Outcomes of an Innovative Protocol for the Treatment of Severe Periodontitis Magda Mensi, Magda Feres, Stefano Calza, Annamaria Sordillo, Eleonora Scotti, Gianluca Garzetti | Download |
| Effect of Adjunctive Probiotic Therapy on the Treatment of Peri-implant Diseases – A Systematic Review Alexandre Pires Silva, Thaís Oliveira Cordeiro, Raíssa Afonso da Costa, Ana Rafaela Luz de Aquino Martins, Euler Maciel Dantas, Bruno César de Vasconcelos Gurgel and Ruthineia Diógenes Alves Uchoa Lins | Download |
| Testosterone Increases Fibroblast Proliferation in vitro Through Androgen and Estrogen Receptor Activation Luis Carlos Leal Santana, Luis Carlos Spolidorio, Jonleno Coutinho Paiva Pitombo, Fernanda Gonçalves Basso, Gabriel Guidio Guarenghi, Rodolfo Coelho Prates, João Paulo Steffens | Download |
