Background: This systematic review evaluated the most effective therapeutic approach to treat periodontal furcation defects with a minimum follow-up of 12 months. The primary outcome was clinical attachment level (CAL). Secondary outcomes were probing pocket depth, gingival margin level, gingival index and plaque index. Methods: A comprehensive search of studies published up to December 2019 and listed in PubMed/MEDLINE, Scopus, and Cochrane Library databases was performed in accordance with the Preferred Reporting Items for Systematic Reviews (PRISMA) statement. Two reviewers independently searched eligible studies, made a final article selection, and extracted the data of the selected studies to evaluate qualitatively and quantitatively (meta-analysis). Results: Overall, 19 studies were selected for the analysis. Six hundred and eighteen patients (mean age, 45.3) were treated. More commonly used treatment was polytetrafluoroethylene barrier (ePTFE), followed by enamel matrix derivative (EMD) and open-flap debridement (OFD). Only one study evaluated maxillary arch and remaining evaluated mandibular arch. All treatments provided CAL gain, but meta-analysis did not show significant difference among more commonly used treatments and controls (P=0.91; P=0.47; P=0.08, respectively). Conclusion: There is no difference on effectiveness of main therapeutic approaches evaluated for treatment of Class II periodontal furcation defects.
|Gingival Crevicular Fluid Levels of Human Beta-defensin 2 and 3 in Healthy and Diseased Sites of Individuals with and without Periodontitis Alexandre Godinho Pereira, Lidiane Cristina Machado Costa, Kahena Rodrigues Soldati, Mauro Henrique Nogueira Guimarães de Abreu, Fernando Oliveira Costa, Daniela Leal Zandim- Barcelos and Luís Otávio Miranda Cota||Download|
|Quality Assessment of Randomized Clinical Trials in Periodontal Research from 2015- 2018 - A Cross Sectional Analysis Abdullah Saleh Al Mutairi and Muzammil||Download|
|Alveolar Ridge Regeneration of Damaged Extraction Sockets using a Bovine-derived Bone Graft in Association with a Titanium Foil: Prospective Case Series Danilo Maeda, Fernando Lima, Jonathan Meza, Danilo Lazzari Ciotti, Fabio Shiniti Mizutani, Helio Doyle, Marcelo Faveri||Download|
|Clinical Evidence for Treatment of Class II Periodontal Furcation Defects. Systematic Review and Meta-analysis Hiskell Fernandes e Oliveira, Fellippo Verri, Cleidiel Aparecido Lemos, Ronaldo Cruz, Victor Eduardo de Souza Batista, Eduardo Pellizzer and Carolina Santinoni||Download|
|One-Stage Full Mouth Instrumentation (OSFMI): Clinical Outcomes of an Innovative Protocol for the Treatment of Severe Periodontitis Magda Mensi, Magda Feres, Stefano Calza, Annamaria Sordillo, Eleonora Scotti, Gianluca Garzetti||Download|
|Effect of Adjunctive Probiotic Therapy on the Treatment of Peri-implant Diseases – A Systematic Review Alexandre Pires Silva, Thaís Oliveira Cordeiro, Raíssa Afonso da Costa, Ana Rafaela Luz de Aquino Martins, Euler Maciel Dantas, Bruno César de Vasconcelos Gurgel and Ruthineia Diógenes Alves Uchoa Lins||Download|
|Testosterone Increases Fibroblast Proliferation in vitro Through Androgen and Estrogen Receptor Activation Luis Carlos Leal Santana, Luis Carlos Spolidorio, Jonleno Coutinho Paiva Pitombo, Fernanda Gonçalves Basso, Gabriel Guidio Guarenghi, Rodolfo Coelho Prates, João Paulo Steffens||Download|