Association of serum vitamin D3 deficiency with stage III periodontitis and periodontal evaluation of deficient individuals after high dose vitamin D3 supplementation

Authors: Resmi Padmom Gopalakrishnan, Ambili Ranjith

Abstract

Aim: The aim of the present study was to find the association between serum vitamin D3 deficiency and stage III periodontitis. The adjunctive benefit of high dose vitamin D3 supplement in periodontal therapy was also evaluated. Methods: Periodontally healthy and diseased individuals (n= 80, age 42.05± 6.7) were included in the study. Serum Vitamin D3 levels were assessed using electro chemiluminescence immunoassay. Vitamin D3 was correlated with full mouth bleeding score and pocket depth using pearson correlation coefficient. After scaling and root debridement vitamin D3 deficient periodontitis patients were provided 60,000 IU Vitamin D3 /week for 8 weeks. Re-evaluation was done after 2 months. Results: Serum Vitamin D3 deficiency was significantly associated with periodontitis with an odds ratio of 16.24 and 95 % confidence interval of 5.39 – 48.91 (p < 0.01). Highly significant correlation was noticed with Vitamin D3 values and full mouth bleeding score and probing depth. Reduction in the periodontal parameters were higher in those who were supplemented with Vitamin D3 compared to non-supplemented group even-though it was not statistically significant. Conclusion: The present study concludes that serum Vitamin D3 insufficiency is significantly associated with periodontitis. Vitamin D supplementation as an adjunct to mechanical therapy needs further evaluation.

Download Article

Other articles in this issue

Article
Evaluation of different clinical periodontal protocols for the treatment of combined endo-periodontal lesions: a clinical and CBCT-based 6-month follow up study Carlos Henrique de Sales Dias Santos, Camila Lopes Ferreira, Naira Maria R B Andere, Cassia Fernandes Araujo, Sergio Lucio Pereira de Castro Lopes, Celso Luiz Caldeira, Mauro Pedrine Santamaria, Maria Aparecida Neves Jardini Download
Comparative clinical evaluation of internal mattress sutures vs continuous independent sling sutures on interdental papilla height and periodontal healing in esthetic zone: Randomized Clinical Study Rashmi Suhag, Nishi Tanwar, Shikha Tewari, Rajinder Kumar Sharma, Satish Chander Narula, Isha Goel Download
Tomographic evaluation of palatal mucosa thickness in donor areas of connective tissue grafts filled with collagen matrix: a randomized split-mouth clinical study Thiago Bezerra da Silva, Mauricio Marcelo Harlos, Mike Reis Bueno, Daiane Cristina Peruzzo, Julio Cesar Joly Download
Levels of angiopoietin 2 and high sensitivity c reactive protein in stage III periodontitis with and without type 2 diabetes mellitus – a cross sectional study Nitish Kalra, Deepesh Jaiswal, Sachin Sinha, Santosh Kumar, Swet Nisha, Mahima Sehgal, Soumya Roychaudhuri, Sonender Pal Singh Download
Association of serum vitamin D3 deficiency with stage III periodontitis and periodontal evaluation of deficient individuals after high dose vitamin D3 supplementation Resmi Padmom Gopalakrishnan, Ambili Ranjith Download
Aesthetic gingival depigmentation with ceramic soft tissue trimming bur and diode laser: a randomized controlled trial Phebie Rodrigues, Joann Pauline George, Roxanne Genevieve Azevedo Download
Volumetric Changes in Anterior Maxillary Reconstruction using DBBM Associated with PRF Membrane and Titanium Mesh – case series Samy Tunchel, Graziele Parize, Alberto Blay, Eduardo Felippe Duailibi Neto, Yeon Jung Kim, Debora Pallos Download
Association of hypothyroidism with periodontal disease complexity Lisa M. Yerke, Elaine L. Davis, Robert E. Cohen Download
Are diagnostic inflammatory biomarkers suitable to predict periodontal disease activity after non-surgical periodontal therapy? Sridharan Srirangarajan, Ranjitha Mohan, Ravi J. Rao, Srikumar Prabhu, Oradiyath Deepika Download
The effect of using of i-PRF (injectable platelet rich fibrin) on filling the gap of immediate dental implant in the esthetic zone”: Randomized clinical trial Bassant Mohye, Mohamed S Al Mofty, Ahmed Y Gamal Download