Introduction: Periodontitis is a chronic infection affecting the supporting tissues of the teeth which, if left untreated, eventually leads to tooth loss. Various grafting materials and barrier membranes have been used to repair periodontal intraosseous lesions. It has been shown that chitosan, a natural polymer, has potential to be used for periodontal tissue regeneration. Thus, it is possible that chitosan, in conjunction with bone grafting, might have good potential to be used for periodontal regeneration. The purpose of this case series was to evaluate the efficacy of chitosan, along with bovine porous bone mineral, in periodontal regeneration of intrabony defects. Materials and Methods: Ten patients aged between 30 and 55 years with intrabony defects ≥3 mm and pocket probing depth (PPD) ≥5 mm were selected. All participants received chitosan gel (15% w/v) plus bovine porous bone mineral as a composite bone graft. Clinical and radiographic measurements were recorded at baseline, 3 months after healing and at 6 and 9 months. Significance was set at 0.05. Results: After nine months, all the defects treated with this combination showed PPD reduction of 5.30 ± 0.822 mm, relative clinical attachment level (CAL) gain of 5.80 ± 0.499 mm, reduction in intrabony defect (IBD) depth of 3.00 ± 0.497 mm and defect resolution of 78.32 ± 5.80 %, all of which were statistically significant. Conclusion: Within the limits of this study, this case series study suggests that chitosan gel, along with bovine porous bone mineral, has a promising role to play in periodontal regeneration.
|Meeting Report: 1st International Academy of Periodontology Research Conference (IAPRC) P. Mark Bartold, Alpdogan Kantarci, Magda Feres, Vincent J Iacono, Joerg Meyle||Download|
|Using a Composite Graft of Natural 15% Chitosan Gel in the Management of Intrabony Defects: A Case Series Irfana Babrawala, Prabhuji MLV and Karthikeyan BV||Download|
|Estimation and Correlation of MMP-8 Levels in GCF and Serum with Wound Healing and Clinical Outcomes of Coronally Advanced Flap and Sub-Epithelial Connective Tissue Graft for Root Coverage - A Controlled Clinical Trial Ankita Jha, Joann P. George and Greeshma Chandrashekhar||Download|
|Clinical and Radiographic Assessment of Single or Combined Treatment with Lepidium sativum and Alendronate of Non-Surgically Treated Chronic Periodontitis in Postmenopausal Osteoporotic Women Naglaa Shawki El Kilani, Hala Helmy Hazzaa, Hisham El Sayed Hemoud and Omenya Imam||Download|
|Periapical Lesion on an Implant after Socket Shield Technique: A Case Report Vitor de Toledo Stuani, Gustavo Gonçalves do Prado Manfredi, Adriana Campos Passanezi Sant’Ana and Maria Lúcia Rubo de Rezende||Download|
|Salivary Levels of Antimicrobial Peptides in Chronic Periodontitis Patients with Type 2 Diabetes A Jameel Ahmed Arshia Zainab, Nichani Ashish and Venugopal Ranganath||Download|
|Occlusal Splints and Periodontal/Implant Therapy Pimchanok Sutthiboonyapan and Hom-Lay Wang||Download|